博落回提取物

主要成分: 血根碱，白屈菜红碱

植物来源: 博落回

规格: 50%/20%

检测：HPLC

外观: 棕红色粉末

分子量: 332.3336/348.3762

分子式: C20H14NO4/C21H18NO4

CAS 号: 2447-54-3/34316-15-9

产品说明：

博落回[( Macleaya cordata( willdl.)R.Br.)]又名号筒管、山麻骨等, 为罂粟科( Papaveraceae) 博落回属多年生亚灌木状草本植物, 根茎特别粗大。它主要分布于我国长江以南、南岭以北,以及甘肃南部等地海拔850m 以下的田野和山坡。博落回在我国药用已有一千多年历史,《本草纲目》、《本草拾遗》、《中药大辞典》、《新编药物学》及《中药志》均有收载,它具有祛风、镇痛、解毒、杀虫、散瘀消肿等功效。国内外研究表明博落回含有种生物碱,它们有杀虫和防病等作用。如能将之开发为一种新型的植物性杀虫剂,对充分利用该植物资源具有重要意义。

博落回中生物碱是抗菌作用的有效成分。博落回水煎剂对多种革兰氏阳性菌和革兰氏阴性菌及钩端螺旋体有较强的抑制作用。乙氧基血根碱和乙氧基白屈菜红碱在体外能抑制革兰氏阳性菌生长,其抑菌作用较黄连素强。白屈菜红碱、血根碱及博落回碱对金黄色葡萄球菌、枯草杆菌、八迭杆菌、大肠杆菌、变形杆菌、绿脓杆菌、某些真菌也有不同程度的抑制作用。乙氧基血根碱在体外对钩端螺旋体也有很强的杀灭作用。博落回有良好的免疫增强功能,动物实验证明,博落回中的生物碱对四氯化碳、半乳糖胺所致急/慢性肝损伤大鼠模型,显示出抑制肝纤维化,保护肝细胞, 改善肝脏功能的作用 。

MacleayaCordataExtract

Active ingredients:Sanguinarine,Chelerythrine

Plantsource:Macleayacordata

Specification: 50%/20%

Testmethod:HPLC

Appearence:Brownish redpowder

M.W: 332.3336/348.3762

M.F: C20H14NO4/C21H18NO4

CAS NO : 2447-54-3/34316-15-9

Introduction    :

Macleaya cordata (Willd) R.Br.,locally called ‘boluhui’, is a perennial plant of thePapaveraceaefamily.It has been used as one of traditional Chinesemedicines(TCMs) for a long time. The herb mainly distributesthroughout thesouth, southeastern and northwest of China, and canalso be foundin middle part ofJapanas well. As reported previously,thealkaloids were considered as main bioactive constituentsofM.cordata. The main alkaloids in this plantincludesanguinarine,chelerythrine, protopine,allocryptopine,dihydrosanguinarine, dihydrochelerythrine,oxysanguinarine,berberine . Contemporary pharmacological studieselucidated thatthe alkaloids exhibited a great variety ofbiological andpharmacological activities such as antitumour ,antibacterial,anthelmintic , and antiinflammatoryproperties.Recentinvestigations in our laboratory have shown that thealkaloids inthe extracts from the plant exhibit certainantioxidantactivity.

Macleayacordata (syn. Bocconiacordata Willd.) is a poisonous plant which isused ornamentally. Macleaya cordata(plume poppy) is a source ofbioactive compounds, mainlyisoquinoline alkaloids which are used inphytopreparations withanti-inflammatory and antimicrobialactivities. The seed oilcontained dihydrosanguinarine,dihydrochelerythrine and twelvefatty acids of which linoleic,oleic, palmitic and stearic acidspredominated